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The doctoral dissertation unveils the interplay between environmental exposure, disease pathology, and immune responses to infections, shedding light on the critical aspects of PM effects on respiratory infections and AD.
Treatment resistance caused by cancer cell plasticity constitutes a major challenge in the treatment of prostate cancer. The SIX2 protein may be a possible factor underlying increased plasticity of prostate cancer cells and treatment resistance.
Ischemic heart disease and heart failure are associated with previously unknown changes in the right atrium of the heart, a new study shows.
The key findings of the doctoral research focus on advancing machine learning (ML) applications for the diagnosis of brain disorders through multimodal neuroimaging data.
These findings underscore the significance of ncRNAs in cardiovascular diseases and provide a better understanding of the roles of miRNAs and ncRNAs in atherosclerosis-related cell types.
The results of this doctoral thesis provide a deeper insight of how endothelial cells react to atherosclerosis promoting conditions.
Two epigenetic drugs were identified in the PhD study as candidates for therapeutic use. An image analysis tool was tested for measuring the vasculature.
The Young Researcher Awards were presented to Adriana Della Pietra, Heli Mutanen, Mervi Rantsi and Matias Rusanen. The Doctoral Supervisor Award was presented to Taina Yli-Juuti.
This thesis work leveraged transcriptomic and lipidomic approaches to unravel cellular and molecular mechanisms underpinning an impaired post-ischemic tissue revascularization and evaluated novel immunomodulatory nanotherapies to rescue this impairment in clinically relevant mouse models.
The University of Eastern Finland awarded Professor Tarja Malm for promoting equality in her research group.